publications

H-index 82 as of September 2022

complete, and most updated, list of published works available at:

Dr Burgess is the co-author of the monthly Highlights in Chemistry and Industry since 1986;
see the Biomedical section of that column.

He is author of three workbooks for teaching:
Organic Chemistry By Inquisition (for graduate students)
Sophomore Organic Chemistry By Inquisition 1 and 2


2022

Conveniently Accessible, Bicyclic ASX Motif Mimics (BAMMs) Inspired by Bioinformatics

T. Mi, K. Burgess

Nat. Chem., 2022, submitted.

Cytoxins of Tumor Seeking Dyes

S. M. Usama, Z. Gao, M. Arancillo, and K. Burgess

Org. Biomol. Chem.2022, submitted

IBM: A New Strategy For PPI Interface Loop Mimicry

T. Mi, K. Burgess

ACS Cent. Sci.2022, submitted

Piptide Chemotypes For Perturbation Of The Interaction Of Urokinase With Its Receptor

M. Arancillo, C. M. Lin, K. Burgess

J. Med. Chem.2022, accepted

IBM: A New Strategy For PPI Interface Loop New, Potent, Small Molecule Agonists of Tyrosine Kinase Receptors Improve Dry Eye Disease

Z. Yu, S. Joy, T. Mi, G. Yazsanpanah, K. Burgess, and C. De Paiva

Front. Med. Opthal..2022, 9, 937142

Synthetic Helical Peptide Capping Strategies

J. Whisenant, K. Burgess

Chem. Soc. Rev.2022, 51, 5795-5804

QuatCy-I2 And MHI-I2 In Photodynamic Therapy

S. Thavornpradit, S. M. Usama, G. K. Park, H. S. Choi, K. Burgess

ACS Med. Chem. Lett.2022, 13, 470-474

A Fluorescent PARP Inhibitor Applied To Intracranial Glioblastoma: Accumulation And Persistence In Vivo

Z. Gao, Z. Yang, Z. Li, K. Burgess

ACS Med. Chem. Lett.2022, 13, 911 – 915

Antibody-Dependent Cellular Phagocytosis of Tropomyosin Receptor Kinase C (TrkC) Ex-pressing Cancer Cells for Targeted Immunotherapy

P. S. Lai, S. M. Usama, L.-V. Kiew, H. B. Lee, L. Y. Chung, K. Burgess, C. S. Kue

Cancer Immunol., Immunother., 2022, 71, 2099-2018

Small Molecule Peptidomimetic Trypsin Inhibitors: Validation Of An EKO Binding Mode, But With A Twist

R.-L. Lyu, S. Joy, C. Packianathan, A. Laganowsky, K. Burgess

Org. Biomol. Chem., 2021, 20, 2075-2080

2021

Fluorescent Kinase Inhibitors As Probes

S. M. Usama, B. Zhao, K. Burgess

Chem. Soc. Rev.2021, 50, 9794-9816

Hows and Whys of Tumor-Seeking Dyes

S. M. Usama, K. Burgess

Acc. Chem. Res.2021, 54, 9, 2121-2131

Flavylium-, And Silylrhoda-polymethines In Excitation Multiplexing

C. Tian, K. Burgess

ChemPhotoChem.2021, 5, 1-4

Preparation of Nano-ZrO2 powder via a microwave-assisted hydrothermal method

Mingyi Guo, Guangxin Wang, Yunchao Zhao, Haitao Li, Kun Tang, Yibo Zhao, Kevin Burgess

Ceramics International2021, 47, 12425-12432

Piptides: New, Easily Accessible Chemotypes For Interactions With Biomolecules

M. Arancillo, J. Taechalertpaisarn, X. Liang, K. Burgess

Angew. Chem. Int. Ed.2021, 60, 6653-6659

Small Molecules Targeting The NEDD8•NAE Protein-Protein Interaction

C. M. Lin, X. Jiang, K. Burgess

Chem. Sci.2021, 12, 1535-15431

Rapid and Visual Detection of Cd2t Based on aza-BODIPY Near Infrared Dye and Its Application in Real and Biological Samples for Environmental Contamination Screening

P. Piyanuch, P. Patawanich, J. Sirirak, K. Buwatpipat, A. Kamkaew, K. Burgess, N. Wanichacheva

J. Hazard. Mater.2021, 409, 124487

2020

Striking Similarities Between CDRs in Some mAbs That Neutralized COVID-19

T. Mi, K. Burgess

ACS Med. Chem. Lett.2020, 11, 1663-1666

Blocking Coronavirus 19 Infection Via the SARS-COV-2 Spike Protein: Initial Steps

J. Whisenant, K. Burgess

ACS Med. Chem. Lett.2020, 11, 1076-1078

Unconventional Secondary Structure Mimics: Ladder-rungs

C. M. Lin, M. Arancillo, J. Whisenant, K. Burgess

Angew. Chem. Int. Ed.2020, 132, 9484-9488

Active Targeted Ligand-AzaBODIPY Conjugate for Near-Infrared Photodynamic Therapy in Melanoma

S. Y. Ng, A. Kamkaew, N. Fu, C. S. Kue, L. Y. Chung, L. V. Kiew, J. Wittayakun, K. Burgess, H. B. Lee

Int. J. Pharm.2020, 579, 119189

Role Of Albumin Binding In Accumulation And Persistence Of Tumor-seeking Cyanine Dyes

S. M. Usama, G. K. Park, S. Nomura; Y. Baek, H. S. Choi, K. Burgess

Mol. Pharm.2020, 21, 248-259

2019

TrkC-Targeted Kinase Inhibitors and PROTACs

B. Zhao and K. Burgess

Mol. Pharm.2019, 16, 4313-4318

Cyanine-Gemcitabine Conjugates as Target Theranostic Agents for Glioblastoma tumor Cells

Z. Jiang, K. Pflug, S. M. Usama, D. Kuai, X. Yan, R. Sitcheran, K. Burgess

J. Med. Chem.2019, 62, 9236-9245

Conjugations of Dasatinib With MHI-148 Has a Significant Advantageous Effect in Viability Assays for Glioblastoma Cells

S. M. Usama, Z. Jiang, K. Pflug, R. Sitcheran, K. Burgess

ChemMedChem2019, 14, 1575-1579

Protein labelling and albumin binding characteristics of the near-IR Cy7 fluorophore, QuatCy

S. Thavornpradit, S. M. Usama, C.-M. Lin, K. Burgess

Org. Biomol. Chem.2019, 17, 7150-7154

Productive Manipulation of Cyanine Dye Pi-Networks

S. M. Usama, T. Thompson, K. Burgess

Angew. Chem. Int. Ed.2019, 28, 2-5

Correlations between secondary structure- and protein–protein interface-mimicry: the interface mimicry hypothesis

J. Taechalertpaisarn, R.-L. Lyu, M. Arancillo, C.-M. Lin, L. Perez, T. Ioerger, K. Burgess

Org. Biomol. Chem.2019, 17, 3267-3274

A Near‐Infrared Fluorescence Chemosensor Based on Isothiocyanate‐Aza‐BODIPY for Cyanide Detection at the Parts per Billion Level: Applications in Buffer Media and Living Cell Imaging

P. Piyanuch, J. Sirirak, A. Kamkaew, O. Weeranantanapa, V. Promarak, K. Burgess, N. Wanichacheva

ChemPlusChem2019, 84, 252-259

Design criteria for minimalist mimics of protein–protein interface segments

J. Taechalertpaisarn, R.-L. Lyu, M. Arancillo, C.-M. Lin, Z. Jiang, L. Perez, T. Ioerger, K. Burgess

Org. Biomol. Chem.2019, 17, 908-915

PROTACs suppression of CDK4/6, crucial kinases for cell cycle regulation in cancer

B. Zhao, K. Burgess

Chem. Commun.2019, 55, 2704-2707

QuatCy: A Heptamethine Cyanine Modification With Improved Characteristics

S. Thavornpradit, S. M. Usama, J. P. Shrestha, G. K. Park, H. S. Choi, K. Burgess

Theranostics2019, 9, 2856-2867

A Near-IR Fluorescent Dasatinib Derivative That Localizes in Cancer Cells

S. M. Usama, B. Zhao, K. Burgess

Bioconjugate Chem2019, 30, 1175-1181

2018

Site-Specific Labeling of Proteins with Near-IR Heptamethine Cyanine Dyes

C.-M. Lin, S. M. Usama, K. Burgess

Molecules2018, 23, 2900

On the Mechanisms of Uptake of Tumor-seeking Cyanine Dyes

S. M. Usama, C.-M. Lin, K. Burgess

Bioconjugate Chem.2018, 29, 3886-2895

A Zwitterionic Near-infrared Dye Linked TrkC Targeting Agent for Imaging Metastatic Breast Cancer

Z. Yang, S. M. Usama, F. Li, K. Burgess, Z. Li

Med. Chem. Comm.2018, 9, 1754-1760

Targeted Maytansinoid Conjugate Improves Therapeutic Index for Metastatic Breast Cacer Cells

Z. Jiang, Z. Yang, F. Li, Z. Li, N. Fishkin, K. Burgess

Bioconjugate Chem.2018, 29, 2920-2926

Optimized Heptamethine Cyanines for Photodynamic Therapy

S. Usama, S. Thavornpradit, K. Burgess

ACS Appl. Bio Mater.2018, 1, 1195-1205

A Click-addressable Cassette for Photoaffinity Labeling

B. Zhao, K. Burgess

ACS Med. Chem. Lett.2018, 9, 155-158


Small Molecule Inhibitors of the PCSK9·LDLR Interaction

J. Taechalertpaisarn, B. Zhao, X. Liang, K. Burgesss

J. Am. Chem. Soc.2018, 140, 3242-3248

2017


Near-infrared aza-BODIPY fluorescent probe for selective Cu2+ detection and its potential in living cell imaging

Y. Tachapermpon, S. Thavornpradit, A. Charoenpanich, J. Sirirak, K. Burgess, N. Wanichacheva

Dalton Transactions2017, 46, 16251-16256

An Agent for Optical Imaging of TrkC-Expressing, Metastatic Breast Cancer

A. Kamkaew, F. Li, Z. Li, K. Burgess

Med. Chem. Commun.2017, 8, 1946-1952

2016

For earlier publications, please check Dr Burgess’ Google Scholar Page.


patents

  • K. Burgess, Inhibitors of LDLR-PCSK9 Protein-Protein Interaction and Methods of Their Use, US Patent No. US10,577,357 B2, World Patent Number WO2018/053517 A1, March, 2020
  • K. Burgess, S. M. Usama, Conjugates of Kinase Inhibitors and Cyanine Dyes, U. S. Patent Application No.: 16/407,264, May 9, 2019, Publication number US-2019-0343958-A1, No-vember 2019
  • K. Burgess, Dipeptide Mimics, Libraries Combining Two Dipeptide Mimics With A Third Group, and Methods For Production Thereof, US Patent No. US99,562,023 B2, February 2017
  • K. Burgess, Peptidomimetic Compounds and Related Methods, US Patent Applica-tion 13866277, Apr 2013.
  • K. Burgess, Through-Bond Energy Transfer Cassettes, Systems and Methods, US Patent No. US 2009/0192298 A1, July 2009.
  • K. Burgess, Dipeptide Mimics, Libraries Combining Two Dipeptide Mimics With a Third Group, and Methods for Production Thereof, US Patent No. US 2009/0264315 A1, October 2009.
  • K. Burgess, Fluorescent Through-Bond Energy Transfer Cassettes Based On Xanthine and Pyronin Derivatives, US Patent No. 7,402,677, July 2008.
  • K. Burgess, Fluorescent Through-Bond Energy Transfer Cassettes Based On Xanthine and Pyronin Derivatives, US Patent No. US 2005/0032120 A1, February 2005.
  • K. Burgess, R. Gibbs, et al., Through Bond Energy Transfer in Fluorescent Dyes for Labelling Biological Molecules, US Patent No. US 6,340,750 B1, January 2002.
  • B. Tamblyn and K. Burgess, New Phosphine Oxazoline Ligand for Chiral Catalysis, US Pa-tent No. US 6472533, December 2002 and Patent MCUS 1455 GB, 1999.
  • H. Uri Saragovi, K. Burgess, β-Turn Peptidomimetic Cyclic Compounds, Patent WO 01/52843 A1, 2001.

books

  • Organic Chemistry By Inquisition, K. Burgess, By Inquisition Press, 2010, 1-600.
  • Solid-Phase Organic Synthesis, K. Burgess, Ed., Wiley & Sons, New York, 2000, 1-277.

book reviews

  • Book review of “Chiral Ferrocenes in Asymmetric Catalysis: Synthesis and Applications”, L.-X. Dai, X.-L. Hou, Eds., Wiley: Weinheim, 2010, J. Am. Chem. Soc., 2010, 132, 10206.
  • Pseudo-Peptides in Drug Discovery (Book Review), K. Burgess, J. Am. Chem. Soc., 2005, 127, 2365.
  • Book review of “Combinatorial Chemistry: Synthesis, Analysis, Screening”, Günther Jung, Ed., Wiley-VCH, New York, 1999, J. Am. Chem. Soc., 2001.
  • Book Review of “Combinatorial Chemistry: Synthesis and Application”, S. R. Wilson, An. W. Czarnik, Eds., Wiley: New York, 1997, 269 pp., Chem. Education Today, 1998, 75, 289.